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Biscoe, North Carolina, is a small but industrious town located in Montgomery County, nestled within the scenic Sandhills region of the state. The area's history dates back to the early 18th and 19th centuries, when settlers of Scottish, Irish, and English descent established farms across the rolling pine-covered landscape. Montgomery County itself was formed in 1779 and has long been known for its natural resources, including fertile soil, timber, and waterways that made early agriculture and milling possible. Before European settlement, Native American tribes such as the Keyauwee and Pee Dee inhabited the region, relying on the land's abundance for sustenance and trade.

Biscoe's growth as a town began in the late 1800s with the expansion of the railroad system across central North Carolina. Originally known as Filo, the town was renamed Biscoe in 1895 in honor of Henry Biscoe, an engineer associated with the Norfolk Southern Railroad. The establishment of the rail line transformed Biscoe into a hub of transportation and commerce, linking rural Montgomery County to larger markets. The railroad encouraged the development of sawmills, textile operations, and small industries that supported the town's early economy. Agriculture also flourished, with local farmers producing cotton, corn, and tobacco that could now be shipped efficiently to neighboring cities.

Throughout the 20th century, Biscoe evolved from a modest railway town into a thriving manufacturing community. The lumber and textile industries became major employers, and the town's proximity to natural resources such as pine forests helped sustain a steady stream of economic activity. With the construction of U.S. Highway 220—later upgraded to Interstate 73/74—Biscoe gained a new layer of connectivity that fostered growth and accessibility. This infrastructure made it easier for residents to commute to surrounding areas and for businesses to expand operations, reinforcing Biscoe's role as a commercial center within Montgomery County.

Community life in Biscoe has long been defined by resilience and small-town pride. Local schools, churches, and civic groups have served as the backbone of the town's culture, promoting education, volunteerism, and strong family values. The town's annual events and gatherings reflect the deep sense of community shared among residents. Even as industries have evolved and modernized, Biscoe has remained committed to preserving its close-knit atmosphere and supporting local enterprise.

Today, Biscoe is a welcoming community that blends its industrial roots with modern suburban growth. Its location along major transportation routes provides convenient access to nearby cities like Asheboro, Pinehurst, and Southern Pines while maintaining the peaceful character of small-town living. With affordable housing, business opportunities, and proximity to outdoor recreation areas like the Uwharrie National Forest, Biscoe continues to attract families and professionals who value a balanced, connected lifestyle. The town stands as a proud example of Montgomery County's enduring spirit—grounded in hard work, tradition, and a shared vision for the future.