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Nestled in the scenic foothills of the Blue Ridge Mountains, Marietta, South Carolina, embodies the tranquil spirit of the Upstate's mountain communities. Before European settlement, the area was part of Cherokee territory, prized for its fertile valleys, dense forests, and proximity to the Middle Saluda River. Early settlers began arriving in the late 18th and early 19th centuries, drawn by the promise of good farmland and abundant natural resources. Families of Scots-Irish and English descent established small farms and homesteads, carving out a rural community that valued independence and hard work. The area was named Marietta in the mid-1800s, likely after a local resident or in tribute to another Southern town, and it quickly became a hub for farmers and traders in northern Greenville County.

Agriculture formed the foundation of Marietta's early economy. The region's rolling hills and mild climate were ideal for growing corn, wheat, and vegetables, while livestock and poultry became important supplements to farm income. Timber was another significant industry, as the surrounding forests provided lumber for homes, barns, and furniture. As the textile boom spread across the Upstate in the late 19th century, Marietta's proximity to Greenville's cotton mills offered employment opportunities while still allowing residents to maintain their rural way of life. Local merchants and craftsmen supported the area's economy, forming the backbone of a self-sustaining, tight-knit community.

Infrastructure improvements in the 20th century brought greater connectivity to Marietta. The creation of U.S. Highway 276, which winds through the town toward Caesars Head and Brevard, North Carolina, opened the community to travelers and outdoor enthusiasts. The highway's scenic views and access to mountain attractions helped transform Marietta into a gateway for tourism in the region. The expansion of utilities, schools, and local services in the mid-1900s further strengthened the community. Though Marietta remained unincorporated, it benefited from the steady economic growth of Greenville County, balancing rural charm with increasing modern conveniences.

Culturally, Marietta has long been known for its strong sense of community and love for the outdoors. The town's proximity to Jones Gap State Park and the Mountain Bridge Wilderness Area makes it a haven for hikers, campers, and nature lovers. Local churches have historically served as gathering places for worship, education, and fellowship, while small family businesses and country stores maintain the friendly character of the area. Annual events and festivals in neighboring communities — such as Travelers Rest's Farmers Market and Slater-Marietta's community gatherings — reflect the region's appreciation for local culture and natural beauty.

Today, Marietta represents the peaceful side of Greenville County living — a blend of rustic charm, natural splendor, and Southern hospitality. Residents enjoy scenic mountain views, clear streams, and a slower pace of life, all within a short drive of Greenville's thriving urban center. New homes and vacation properties are appearing alongside historic farmhouses, as more families and retirees discover the area's appeal. Marietta continues to balance growth with preservation, maintaining its identity as one of South Carolina's most serene and picturesque communities.