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The town of West Union, South Carolina, is situated in the foothills of the Blue Ridge Mountains and is one of the charming small towns that define Oconee County's historical and cultural richness. The area that would become West Union was originally part of Cherokee territory before European settlers began to arrive in the 18th century. Early pioneers were drawn to the region's fertile land, abundant waterways, and the natural beauty of the surrounding hills. When Oconee County was carved from Pickens County in 1868, the region around present-day West Union began to develop as a small farming and trade community. The town's name, "West Union," likely reflects its location west of nearby Walhalla, the county seat, and its role as a connecting settlement in the foothill trade routes of upstate South Carolina.

Agriculture was the foundation of West Union's early economy. Like much of the Upstate, the community's landscape was dotted with small family farms producing cotton, corn, and livestock. The arrival of textile mills in the late 19th and early 20th centuries brought new economic opportunities to Oconee County, including the nearby towns of Seneca and Walhalla. Many residents of West Union found employment in these industries while maintaining agricultural ties. Cotton gins, general stores, and blacksmith shops supported the local economy, creating a self-sufficient community that thrived on the hard work and resilience of its people. The town's growth was steady rather than rapid, preserving its rural charm even as industrialization expanded across the Upstate.

Infrastructure improvements in the 20th century helped connect West Union more closely with the surrounding region. The establishment of major roadways such as South Carolina Highway 28 and Highway 183 linked the town with Seneca, Walhalla, and Westminster, making travel and trade more efficient. Rail lines running through Oconee County provided additional avenues for transporting goods, particularly agricultural and textile products. The proximity of West Union to Lake Keowee and Lake Jocassee—reservoirs created by Duke Energy in the mid-20th century—brought further development and recreational appeal to the area. These man-made lakes not only provided hydroelectric power but also transformed the landscape, attracting tourism, new housing developments, and outdoor enthusiasts.

Culturally, West Union reflects the strong community values typical of small Southern towns. Its residents take pride in their history, with deep family roots and traditions that have been passed down for generations. Churches and schools have long served as the social and spiritual centers of town life, while local events and gatherings foster a sense of unity. The surrounding Oconee County is known for its rich musical heritage, particularly in bluegrass and Appalachian folk traditions, which have influenced the culture of West Union as well. The town's close proximity to Walhalla—home of the annual Oktoberfest celebrating the area's German immigrant roots—further connects West Union to the broader cultural fabric of the Upstate region.

Today, West Union is a peaceful and picturesque community that offers a blend of small-town tranquility and modern convenience. Its location near the scenic Blue Ridge Mountains and Lake Keowee makes it an appealing place for families, retirees, and those seeking outdoor recreation. Residents enjoy easy access to hiking trails, waterfalls, fishing, and boating opportunities, as well as the amenities of nearby Seneca and Clemson. The area's strong sense of community, combined with its natural beauty and growing economy, continues to make West Union an attractive place to live and work. Balancing history and progress, this town exemplifies the enduring spirit of Oconee County—quiet, welcoming, and full of Southern character.